| Rune of Tempest | a stonemite | Sewers of Nihilia, Purifying Plant | — |
| Rune of Tempest | a viscous ooze | Sewers of Nihilia, Purifying Plant | — |
| Rune of Tempest | a bloodthirsty stonemite | Sewers of Nihilia, Purifying Plant | — |
| Rune of Tempest | a vicious turepta | Sewers of Nihilia, Purifying Plant | — |
| Rune of Tempest | a fading worker | Sewers of Nihilia, Purifying Plant | — |
| Rune of Vortex | Unknown Vendor | Multiple Zones | — |
| Rune of the Astral | Unknown Vendor | Multiple Zones | — |
| Rune of the Cyclone | Unknown Vendor | Multiple Zones | — |
| Rune of the Inverse | Unknown Vendor | Multiple Zones | — |
| Runed Glyph: Aexit | Altar Warden | Ikkinz, Chambers of Destruction | — |
| Runed Glyph: Grexit | Altar Warden | Ikkinz, Chambers of Destruction | — |
| Runed Glyph: Noxit | Altar Warden | Ikkinz, Chambers of Destruction | — |
| Runed Glyph: Truxit | Altar Warden | Ikkinz, Chambers of Destruction | — |
| Runic Charta Arcanum Solution | Nursa Rasumus | Plane of Knowledge | — |
| Runic Charta Arcanum Solution | a spell research merchant | Halas | — |
| Runic Charta Arcanum Solution | a spell research merchant | North Kaladim | — |
| Runic Charta Arcanum Solution | a spell research merchant | Neriak - Commons | — |
| Runic Charta Arcanum Solution | a spell research merchant | Kelethin (in Greater Faydark) | — |
| Runic Charta Arcanum Solution | Morris Addel | Abysmal Sea | — |
| Runic Charta Arcanum Solution | a clockwork merchant | Ak'Anon | — |
| Runic Charta Arcanum Solution | a spell research merchant | Ak'Anon | — |
| Runic Charta Arcanum Solution | a spell research merchant | Grobb | — |
| Runic Charta Arcanum Solution | a spell research merchant | Erudin | — |
| Runic Charta Arcanum Solution | a spell research merchant | East Cabilis | — |
| Runic Charta Arcanum Solution | Researcher Melka | Crescent Reach | — |
| Runic Charta Arcanum Solution | Researcher Junna | Crescent Reach | — |
| Runic Charta Arcanum Solution | Researcher Kakra | Crescent Reach | — |
| Runic Charta Arcanum Solution | a spell research merchant | Crescent Reach | — |
| Runic Charta Arcanum Solution | Merchant Model CGXXII | Corathus Creep | — |
| Runic Charta Arcanum Solution | Merchant Model CGXVIII | Corathus Creep | — |
| Runic Charta Arcanum Solution | Merchant Model CGXXIV | Corathus Creep | — |
| Runic Charta Arcanum Solution | Ostasy Atquai | Abysmal Sea | — |
| Runic Charta Arcanum Solution | a spell research merchant | Oggok | — |
| Runic Charta Arcanum Solution | Scholar Klaz | Plane of Knowledge | — |
| Runic Charta Arcanum Solution | Sansus Rasumus | Plane of Knowledge | — |
| Runic Charta Arcanum Solution | Maree Rasumus | Plane of Knowledge | — |
| Runic Charta Arcanum Solution | a spell research merchant | Rathe Mountains (see also Gukta) | — |
| Runic Charta Arcanum Solution | Ngroth at +914, +472, -274 | Relic, the Artifact City | — |
| Runic Charta Arcanum Solution | Krack at +947, +552, -274 | Relic, the Artifact City | — |
| Runic Charta Arcanum Solution | Myath at +943, +533, -274 | Relic, the Artifact City | — |
| Runic Charta Arcanum Solution | a spell research merchant | Rivervale | — |
| Runic Charta Arcanum Solution | a spell research merchant | Shar Vahl | — |
| Runic Charta Arcanum Solution | a spell research merchant | South Qeynos | — |
| Runic Charta Arcanum Solution | a spell research merchant | Southern Felwithe | — |
| Runic Charta Arcanum Solution | Merchant Jewyln | Southern Felwithe | — |
| Runic Charta Arcanum Solution | Visar Glolith | West Cabilis | — |
| Runic Charta Arcanum Solution | a spell research merchant | West Freeport | — |
| Runic Hide Solution | a spell research merchant | Kelethin (in Greater Faydark) | — |
| Runic Hide Solution | a spell research merchant | Halas | — |
| Runic Hide Solution | a spell research merchant | Grobb | — |
