| Sand Wasp Larvae | Roots | Takish-Hiz: The Sandfall Corridors | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Prismatic Corridors | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Sunken Library | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Sweeping Tides | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Royal Observatory | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Balancing Chamber | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The River of Recollection | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Antiquated Palace | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Fading Temple | — |
| Sand Wasp Larvae | Roots | Takish-Hiz: The Shifting Tower | — |
| Sarnak Blood | various sarnaks | Lake of Ill Omen | — |
| Sarnak Blood | sarnaks | Karnor's Castle | — |
| Sarnak Blood | sarnaks | Warsliks Woods | — |
| Sarnak Blood | sarnaks | The Overthere | — |
| Sarnak Blood | a sarnak recruit | Lake of Ill Omen | — |
| Sarnak Blood | a Sarnak zealot | Burning Woods | — |
| Sarnak Blood | a sarnak champion | Burning Woods | — |
| Sarnak Blood | a Sarnak knight | Burning Woods | — |
| Sarnak Blood | various kly | Crypt of Dalnir | — |
| Sarnak Blood | sarnaks | Frontier Mountains | — |
| Scorpion Blood | a scorpion | Shar Vahl | — |
| Scorpion Blood | a whiptail scorpion | Shar Vahl | — |
| Sea-Foam Sugar | Assistant Jeyular | Ocean of Tears | — |
| Seahorse Roe | a kerra snake | Erud's Crossing | — |
| Seahorse Roe | a seahorse | Erud's Crossing | — |
| Seahorse Roe | Fruit | Erud's Crossing | — |
| Seahorse Roe | a kerra spider | Erud's Crossing | — |
| Seahorse Scales | a swirlspine seahorse | Kedge Keep | — |
| Seahorse Scales | a coldspine seahorse | Siren's Grotto | — |
| Seahorse Scales | a spinereef seahorse | Kedge Keep | — |
| Shade Fungus | Fruit | Hills of Shade | — |
| Shiknar Ichor | shik'nar | Fungus Grove | — |
| Shimmering Fairy Drake Dust | a serene mist drake | Sunderock Springs | — |
| Shimmering Fairy Dust | a wind nymph | Dragonscale Hills | — |
| Shissar Blood | Commander Zherozsh (Named Shissar) | Ssraeshza Temple | — |
| Shissar Blood | shissars | Ssraeshza Temple | — |
| Short Beer | Volkoon D`Dbth | Neriak - Commons | — |
| Short Beer | Bull Crusher | Neriak - Foreign Quarter | — |
| Short Beer | Damar Nislan | Neriak - Foreign Quarter | — |
| Short Beer | Darien Felton | Neriak - Foreign Quarter | — |
| Short Beer | Sera Buelle | Neriak - Foreign Quarter | — |
| Short Beer | Slunga | Neriak - Foreign Quarter | — |
| Short Beer | Jaeger Mort | Sanctus Seru | — |
| Short Beer | a goblin bartender | Runnyeye Citadel | — |
| Short Beer | Sven Drinn | Rathe Mountains (see also Gukta) | — |
| Short Beer | Philicia Drinn | Rathe Mountains (see also Gukta) | — |
| Short Beer | Innkeep Troy | Rathe Mountains (see also Gukta) | — |
| Short Beer | Innkeep Serge | Rathe Mountains (see also Gukta) | — |
| Short Beer | Klen Ironstove | Plane of Knowledge | — |
| Short Beer | Culkin Ironstove | Plane of Knowledge | — |
